Skin Cancer is the most common of all cancers. Over one million Americans develop skin cancer every year. Overexposure to the sunlight including tanning is the main cause of skin cancer especially when it results in sunburn and blistering. Other less important factors include repeated medical and industrial x-ray exposure, scarring from disease and/or burns, occupational exposure to such compounds as coal and arsenic, and a family history of skin cancer. Fair-skinned people who sunburn easily are at particularly high risk for skin cancer.